Big Brain Holdings

Crypto Asset Management·United States·bigbrain.holdings

About Big Brain Holdings

Big Brain Holdings is a global multi-stage investment firm that backs funds and founders operating at the intersection of artificial intelligence, robotics, decentralized infrastructure, and consumer technology. The firm takes concentrated, long-term positions in companies pursuing what it describes as radical ideas rooted in first-principles thinking and cypherpunk values. Its portfolio spans more than 120 companies and 60 funds across 40 countries, with holdings including Solana, NEAR Protocol, Mysten Labs, Flashbots, Apptronik, Agility Robotics, and Hyperbolic, among others. Big Brain Holdings targets founders working on foundation models, AI inference infrastructure, humanoid robotics, decentralized compute networks, and deep-technology problems.

Signal snapshot

PULSE

last updated 8 Nov 2026

Current state across team, hiring, social, web and news.

TEAM SIZE

around 15category median under 10

estimated · weekly

TRACKED OPEN ROLES

none tracked

jobs pipeline · daily

X FOLLOWERS

30,927▼105 · 30d

X · daily

WEB AUTHORITY

201,156 referring domains

web data · monthly

Alerts when these signals move, plus history and comparisons: Pulse.Join the waitlist →

More in Crypto Asset Management

View all →

Karatage

Crypto Asset Management

Karatage is a pioneering hedge fund specializing in investments within the cryptocurrency ecosystem. Founded in 2017, Karatage has been at the forefront of the crypto revolution, identifying and capitalizing on emerging trends and opportunities. The firm employs a sophisticated investment strategy that encompasses a diverse range of crypto assets, including cryptocurrencies, blockchain-based projects, and innovative companies that are transforming industries through the power of blockchain technology. Karatage's team of experienced investment professionals conducts rigorous research and analysis to identify promising investment opportunities and navigate the dynamic and evolving crypto landscape.

Digital Currency Group

Crypto Asset Management

Digital Currency Group is a global leader in blockchain and digital currency. They build and support companies using our network, insights, and access to capital. Their mission is to accelerate the growth of the blockchain and digital currency industries. DCG has been at the forefront of this industry since its inception, investing early in some of the world’s leading digital currency companies such as Coinbase, Ripple, BitPay, and Circle Internet Financial. Today, they continue to invest in top talent and help create an environment where these companies can thrive.

Ondo Finance

Crypto Asset Management

Ondo Finance is a blockchain-focused financial infrastructure company that builds institutional-grade platforms, assets, and infrastructure to bring traditional financial markets onchain. Its core product line includes tokenized real-world assets such as U.S. Treasury funds and tokenized stocks, with the company offering 24/7 minting and redemption capabilities for these instruments. The platform is designed for institutional participants and operates across multiple blockchain networks including Ethereum, Solana, Aptos, and Sui. Ondo has conducted cross-border, cross-bank redemption pilots for tokenized U.S. Treasury funds in collaboration with major financial institutions, and has integrated voting capabilities for tokenized stocks through a partnership with Broadridge.